And, there are some things you can do to limit or ease the nausea to make it more manageable
It states plainly that higher doses do not automatically produce better outcomes

[15] Coverage may continue for type 2 diabetes indication Separate from Highmark policies in PA What This Means for You Check your specific plan: Coverage varies by state, employer, and plan typedon't assume During open enrollment: If your BCBS plan is dropping coverage, explore other insurer options Self-funded employers: Ask HR if your employer is opting to continue GLP-1 coverage Consider alternatives: If you have Type 2 diabetes, Mounjaro (same active ingredient) may still be covered CV indication not yet covered: Despite Lilly's cardiovascular benefits data, no BCBS plans currently cover Zepbound for heart disease or CV risk reductionmost explicitly exclude it [16] CALL YOUR INSURANCE Verify Your Specific Coverage Verify Your Specific Coverage Even though it takes a little more time, we recommend calling so you can speak with a person who may have more information than the online directory or PDF formulary listing

This is consistent with research suggesting that these drugs broadly reduce neuroinflammation, which may also be a mechanism through which they improve anxiety and depression and reduce suicidality
That complex has a half-life of many hours, but the IGF-1 it carries is not free to bind IGF1R while complexed