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Diabetes - GLP-1 agonists should be primarily considered in patients with type 2 diabetes with suboptimal glycaemic control despite maximal tolerated dose of metformin (+/- other agents) especially where weight loss is desired and/or significant stroke risk is present

No, microdosing is an off-label practice and is not officially recommended by regulatory bodies such as the U.S

The amount of coffee is identical

This process can take months or longer

Short-acting GLP-1 RAs also have a more pronounced effect on satiety with a meal (since food stays in stomach longer), but long-acting ones affect the brain continuously to reduce appetite