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Increased epigenetic marks (H3K27ac, H3K4me3, H3K4me1) were associated with primed-microglia in Parkinson's disease (Huang et al., 2023) and AD (Wendeln et al., 2018), and glycolysis/H4K12la/PKM2 positive feedback loop exacerbated microglial dysfunction (Pan et al., 2022)

10.1681/ASN.2018111126 102 SunY.GeX.LiX.HeJ.WeiX.DuJ.et al (2020)

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