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53 One study compared various scoring systems, including the KCH criteria, the sequential organ failure assessment (SOFA), the MELD and the acute physiology and chronic health evaluation II (APACHE II), as prognostic indicators for their ability to reduce mortality rates due to APAP hepatotoxicity

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Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP

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doi:10.1007/s13762-016-1000-9 Pai NR, Dubhashi DS (2013) Development of stability indicating, validated HPLC method for quantitative determination of aripiprazole and its impurities