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however, no formal evaluation for Cushing syndrome (eg, urinary free cortisol, dexamethasone suppression testing, or late-night salivary cortisol) was required for enrollment in the oncology study

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Specifically, changing the Val229 residue to alanine, selected in this study for further investigation, was predicted to trigger a change in the cavity and a buried exposure switch at the inactive receptor, thereby potentially modifying the interactions between itself and other pocket residues with cholesterol

Effect of vitamins B1, B6, B12, and C on the motor activity of the stomach, small and large intestines in patients with chronic enterocolitis and colitis