HbA 1c was reduced in SURPASS 15, using from 5 to 15 mg of TZP per week, by between 1.69 to 2.58%, and a new plateau of HbA 1c and fasting serum glucose (FSG) was reached with approximately 2430 weeks of treatment
Some experience this at starting doses, she notes, adding that she has many patients who have lost significant weight without ever escalating the dose
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