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The clinical evidence behind them is unusually strong: in large randomized trials, semaglutide produced about 14.9% mean weight loss over 68 weeks and high-dose tirzepatide up to about 20.9% over 72 weeks

Furthermore, POD was only down-regulated in response to WCM infestation (Fig

In a 40-week clinical trial, participants who took Tirzepatide 5.0 mg lost 7.0 kg of body weight, participants who took Tirzepatide 10 mg lost 7.8 kg of body weight, and participants who took Tirzepatide 15 mg lost 9.5 kg of body weight

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