The proven cardiovascular benefits of semaglutide, particularly the reduction in major adverse cardiovascular events demonstrated in the SELECT trial, also influence the decision for those with heart disease risk factors
AOD-9604 is a modified form of amino acids 176-191 of the Growth Hormone (GH) polypeptide
2024;doi:10.1056/NEJMoa2403347) demonstrated that addition of semaglutide (Ozempic/Wegovy, Novo Nordisk) to an SGLT2 inhibitor showed no renal protective effect (HR = 1.07, 95% CI 0.69-1.67), although the number of subjects receiving an SGLT2 (16%) in this study was relatively small
Food-first approach Rather than relying solely on supplements, focus on a nutrient-rich diet that naturally supports collagen production: Protein-rich foods : Meat, fish, eggs, dairy, tofu, and legumes Vitamin C sources : Berries, peppers, leafy greens, and citrus fruits Minerals : Zinc (seafood, meat, nuts) and copper (shellfish, nuts, seeds) Bone broth : Contains naturally occurring collagen and other beneficial compounds If youre unsure what a balanced diet based on whole foods looks like, the Second Nature balanced plate model is a good place to start
For medispa professionals : Establish protocols for supporting clients using peptide therapies, including symptom tracking systems and lifestyle optimization frameworks