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Some emphasize probiotics

Although the function of CHCHD2 has not been fully elucidated, studies have reported that CHCHD2 expression affected the activity of complex I and complex IV, mitochondrial biogenesis, mitochondrial stability, and cristae structure (Wei et al., 2015

Dose adjustment should only be considered after optimizing dietary protocol, injection technique, and lifestyle factors

2) inflammation

Kislinger T, Fu C, Huber B, Qu W, Taguchi A, Du Yan S, Hofmann M, Yan SF, Pischetsrieder M, Stern D, et al: N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression