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Trends Pharmacol Sci 17: 348355

While typically associated with oxidative stress conditions, glutathionylation also occurs under basal physiological conditions, especially during the regulation or regeneration of thiol-containing enzymes like peroxidases

The conjugation of free paracetamol to either the glutathione or the glucose conjugate is a rapid process: all conjugation products are present right after 3 h of incubation