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Among the 56 patients with complete follow-up data at 1 year, there was a significant improvement in weight-related comorbidities, including a reduction in obstructive sleep apnea syndrome ( 30%), hypertension ( 40%), arthralgia ( 56.5%), and fatty liver disease ( 36.4%)

SPF-FUS mice were then subjected to the OFT, and food intake was evaluated (Supplementary Fig

20% reduction in MACE vs

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Routine consultation is appropriate for persistent changes in urine odor lasting more than two weeks, especially if accompanied by unexplained weight loss beyond expected parameters, persistent nausea affecting hydration, or concerns about nutritional adequacy