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Not just the gut
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Beyond this, we are conducting a clinical trial exploring the combination of a GLP-1 therapy with muscle-preserving antibodies for the treatment of obesity
In 2024, the Biden administration proposed a rulethat would have aligned coverage policy to reflect the prevailing medical consensus that obesity is a chronic disease, thereby rendering treatment of obesity as a medically necessary service under Medicare
Mechanistically, cancer cells capable of inducing cancer cachexia are secreting IL-6, which subsequently induces autophagy in differentiated muscle cells via IL-6 signaling and therefore might be relevant for the characteristic muscle and weight loss during cancer cachexia (276)
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