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Curcumin, well documented for its potent anti-inflammatory activity also acts on Nrf2 and leads to improved total antioxidant capacity and an increase in endogenous anti-oxidant production, such as catalase, but only when retained as the free form
As long as you have the time of ingestion and the serum acetaminophen level, then using the Rumack-Matthew nomogram to decide when to treat an acetaminophen overdose/toxicity is super easy
