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The EM structure of Tirzepatide bound to the complete GLP-1R and G-proteins (Figure 2, PDB ID 7rgp , Sun et al., 2022) shows some hydrophobic and some specific polar interactions between the peptidic drug and the GLP-1 receptor molecule
Simulations of Target Acquisition with MIRI Four-quadrant Phase Mask Coronagraph (I) , Report JWST-STScI-003063, SM-12 (STSI, 2013)
Constipation from slower gastric transit
Frontiers in nutrition, 9, 868640
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