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Moreover, the decreased thrombomodulin-dependent activation of protein C observed in hyperhomocysteinemic primates suggests that a moderate increase in circulating homocysteine alters endothelial antithrombotic properties (Lentz et al, 1996)

Early diagnosis and treatment of obesity, hypertension and dyslipidemia were also stated to be of major importance in this population

Riphagen S, Gomez X, Gonzalez-Martinez C, et al

Clinical implication Clinicians are encouraged to perform comprehensive evaluations prior to prescribing GLP-1 RA therapy in patients with a history of pancreatic disorders or other pancreatitis risk factors

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