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Because the extracellular matrix (ECM) controls ventricular geometry, compliance, and electrical continuity, even small but chronic shifts in its turnover have large mechanical effects

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Cattle raised in conventional feedlot conditions, fed grain, and treated with growth hormones and antibiotics produce biochemically different collagen than cattle raised on pasture in grass-fed systems

However, we showed previously that fasting total GLP-1 concentrations correlate strongly with fasting glucagon, raising the possibility that this might be attributable to total GLP-1 assays also detecting GLP-1(1-36amide), an inactive peptide produced from proglucagon processing in pancreatic alpha cells and co-secreted with glucagon