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Semaglutide treatment over four months led to a weight reduction of 5 kg, from 118 kg (BMI 55 kg/m 2 ) to 113 kg (BMI 52.7 kg/m 2 )

Newsome PN, Buchholtz K, Cusi K et al (2021) A placebo-controlled trial of subcutaneous semaglutide in nonalcoholic steatohepatitis

Compared with these previous studies, our results indicate that both FLVCR1 and FLVCR2 prefer choline as a substrate to ethanolamine

However, appetite hormones typically normalize within weeks to months after discontinuation, making continuous therapy the most reliable strategy for long-term weight management

Ruolo clinico: utile in soggetti con alimentazione compulsiva e craving, previa valutazione psichiatrica e cardiovascolare accurata.