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Although patent protection lapsed in 2019, various settlement agreements continued to moderate generic impact, with increased generic volumes in 2025 contributing to a sharper slowdown in growth prior to unrestricted competition in 2026

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GLP-1RAs consistently demonstrate neuroprotective effects in AD models

Brain-derived neurotrophic factor (BDNF) (276), brain-derived exosomes (277), and other plasma brain-derived ASD biomarkers, have been discovered in numerous research