Each mL contains: Thiamine Hydrochloride 100 mg, Riboflavin 5 Phosphate Sodium 2 mg, Pyridoxine Hydrochloride 2 mg, Dexpanthenol 2 mg, Niacinamide 100 mg, with Benzyl Alcohol 2% as preservative, in Water for Injection
These treatment conditions were chosen to mimic excess heme from chronic hemolysis and systemic hypoxic conditions that occur in SCD patients 1,2,11
Recent studies indicate that Aspergillus fumigatus infection can induce mtDNA leakage into the cytosol, activating cGAS-STING signaling and type I interferon production (Peng et al., 2023)
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It helps repair muscle damage and clears metabolic waste products like lactic acid