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The step 8 clinical trial involved 338 individuals to compare the effect of weekly subcutaneous semaglutide vs liraglutide (daily) in obese and overweight patients without type 2 diabetes

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Peak LH concentrations were significantly higher in the C group with an average of 6.6 1.4 ng/mL than in the FE and FA groups with averages of 4.7 0.8 ng/mL and 3.8 0.5 ng/mL, respectively, with no significant difference between FE and FA