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Association of Prenatal Acetaminophen Exposure Measured in Meconium with Risk of Attention-Deficit/Hyperactivity Disorder Mediated by Frontoparietal Network Brain Connectivity

We then focused on the entire list of miR-4488-down-regulated genes irrespective of their cluster origin, ending up with a set of 409 genes that were significantly down-regulated (t = 48 miR-4488 versus t = 48 miR-CTRL, fold change of 1.5 or less and q-value of 0.05 or less)

However, its clinical application has been limited by dose-dependent gastrointestinal toxicity observed in later phase I and II clinical trials

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