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5.4 Postbiotics According to International Scientific Association of Probiotics and Prebiotics (ISAPP), postbiotics are described as preparation of inanimate microorganisms and/or their components that confers a health benefit on the host (252)

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Furthermore, the endogenous peptide Agouti-related peptide (AgRP), which is an inverse agonist on MC4R and a competitive antagonist or ERK-biased agonist on MC3R, is known to increase food intake and body weight (30, 31)