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Considering the potential appetite-reducing effects of GLP-1 RAs, diet-restricted control groups were included for both drugs, ensuring consistent food intake between treatment and control groups, thereby minimizing any dietary bias
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By 6-12 months of consistent therapy, glutathione levels typically stabilize at elevated baselines that reflect the supplementation protocol while accommodating individual metabolic factors affecting glutathione turnover
BMC Evol Biol 18:122
Known type 2 diabetes mellitus agents such as metformin, thiazolidinediones (TZDs), sulfonylureas, or basal insulin may also be considered
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