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South Park parodied the drug in a special titled The End of Obesity , while Oprah Winfrey hosted a primetime special on the drug

Tirzepatide is a dual receptor co-agonist that also activates GLP-1 but goes a step further by targeting a second hormone called GIP (glucose-dependent insulinotropic polypeptide)

Multiple sessions may be needed for optimal results, which can be assessed with your healthcare provider

Extended-release berberine at 1000mg twice daily is an alternative that provides similar total daily exposure with fewer dosing events and often better GI tolerability

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