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Measure baseline weight, BMI, vital signs, and labs (fasting lipids, fasting glucose or )

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Because ipamorelin and GHRH analogs act through separate receptor pathways (GHS-R1a versus the GHRH receptor), preclinical research has investigated the two compound classes together, hypothesizing that dual-pathway stimulation may produce additive or synergistic effects on GH release compared with either pathway alone a design that leverages the cAMP/calcium signaling distinction described above

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In this study, 57.1% of patients were initiated at a dose higher than 3 mg, with most patients initiated on a 7 mg dose