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The mechanism appears to involve increased serotonin synthesis in substantia nigra (both compacta and reticulata), a regional pattern unlike any existing antidepressant drug, plus potential dopaminergic contributions given the nigrostriatal location

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A 2023 analysis of GLP-1 users found that those prioritizing 2535 grams of protein per meal maintained muscle mass during weight loss, while low-protein eaters lost an average of 24 pounds of muscle tissue per 10 pounds of fat loss

The Journal of Steroid Biochemistry and Molecular Biology

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