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Typical protocol: Dose: 12 mg subcutaneously daily Duration: 812 weeks for visible skin changes Can also be used topically (0.51% in carrier solution) KPV: The Targeted Anti-Inflammatory KPV is a tripeptide (lysine-proline-valine) derived from alpha-MSH (alpha-melanocyte-stimulating hormone)
Note that semiquinone radicals can possess extremely long half-lives, up to days at 37 C 35 , and as such, it is unsurprising that SQ . is present over 30 minutes in the model (Fig
In most, daily doses just below 100mg are where significant effects begin
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They are not dosing recommendations for humans, and no application dose can be derived from them
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