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Inhibition of ASCT2-mediated GLN uptake in human cells using a lead compound (V-9302) resulted in attenuation of cancer cell growth and proliferation, frequent cell death, and increased oxidative stress [28]

Certain phytochemicals may produce adverse effects, including local skin irritation, allergic reactions, and, in some cases, systemic toxicity, particularly with prolonged use or high doses

Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction

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