Bajaj 5 , Rachel Bachrach 2,6 , Ponni Perumalswami 7,8 and Shari S
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4 Haem-iron is an important mediator of NTHi pathogenesis and persistence The success of NTHi as a pathogen is reliant on its ability to perform interactions with the host, many of which are regulated directly or indirectly by the bioavailability of haem or other iron-containing moieties (Harrison et al., 2013)
A high-content screening assay can be utilized to analyze lysosomotropic substrates, allowing for toxicology screening to identify oncological therapeutics with lysosomotropic properties to be performed using this method (268)
