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Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice

Key points: Both medications cause similar gastrointestinal side effects, most commonly nausea, diarrhoea, and constipation In the head-to-head trial, liraglutide had double the discontinuation rate of semaglutide (27.6% vs 13.5%) Side effects tend to occur early in treatment and improve over time Wegovy has cardiovascular outcome data (SELECT trial) that liraglutide does not Dosing and practical differences Injection frequency One of the most significant practical differences is how often you inject