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Keywords Tetrabenazine Trade Name: Xenazine Drug Class: Rx of Huntington's chorea (monoamine depletor) Mechanism of Action: the vesicular monoamine transporter isoform expressed in the CNS and sympathetic nervous system that is responsible for movement of monoamines (norepinephrine, dopamine, serotonin & histamine)from the cytoplasm into presynaptic storage (Headley et al, 2006)