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Secretory IgA (sIgA) measured in stool assesses the gut immune barrier

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Various microbial species exhibited correlations with BMD and T-scores across multiple skeletal locations

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Number of clinical and experimental studies demonstrated its importance as a dietary supplement in maintaining gastrointestinal mucosal barrier function and in preventing bacterial and endotoxin translocation during parenteral nutrition, sepsis, infection, radiation and other various catabolic stress conditions