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doi: 10.1016/s0029-7844(00)00822-x 178 TamuraHTakasakiAMiwaITaniguchiKMaekawaRAsadaHet al

Studies in animal models, such as streptozotocin (STZ)-induced diabetic rodents, demonstrate that mitochondrial-targeting antioxidants like mitoquinone (MitoQ) can partially restore mitochondrial function and alleviate neuropathic symptoms [49]

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Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure

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