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For the newer GLP-1 medications, it would be useful to look at whether there are genetic variants, like the variants in PAM, that explain poor responders to their medications. Although the underlying biological mechanism remains poorly understood, Gloyn believes GLP-1 resistance is likely driven by a complex interplay of factors rather than a single cause

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So it is one of those things you think, wow, that-thats a thats a almost an easy fix as a public health issue

But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room

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