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Guo et al., 2022

It is a clinical pathway you qualify for based on findings

Losing muscle (or lean mass) is a common side effect of weight loss in adults with obesity and may negatively affect metabolism and bone health

In general, the most distinct clinical features (summarized in Table 1 ) include: (i) a recognizable orofacial gestalt at birth with swelling of the periorbital soft tissues, blue sclerae, down-slanting palpebral fissures, epicanthic folds, micrognathia, delayed fontanel closure, and dental anomalies in childhood and adulthood