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[19] [20] The rate and magnitude of glycemic deterioration depend on individual factors including baseline diabetes severity, duration of disease, beta-cell function, and lifestyle factors

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Furthermore, sulforaphane-treated CIA mice presented reduced levels of type II collagen-specific IgG, IgG1, and IgG2a antibodies in the circulation, confirming that sulforaphane inhibited B-cell differentiation into antibody-producing plasma cells in a context that also inhibited proinflammatory cytokine production

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