This suggests a real, measurable effect on bone that warrants monitoring and protective interventions, particularly for patients who are already at risk for osteoporosis
The NDN gene encodes necdin, a member of the MAGE protein family that is mainly expressed in the brain
Other major players, which include AstraZeneca, Pfizer, Sanofi, Roche, Amgen, and Boehringer Ingelheim, are expanding pipelines via innovation, acquisitions, and partnerships
The glucose-dependent insulin secretion mechanism of GLP-1R and GIPR agonism means that insulin release is amplified only when blood glucose is elevated, reducing the risk of hypoglycaemia compared to insulin or sulfonylurea-based interventions
it remains to be seen how it will fare in the current Congress