Treatments launched in the past several years by companies including Eli Lilly and an Eisai-Biogen partnership are the first drugs ever shown to slow cognitive decline in people with Alzheimers after years of failed trials, but they require infusions or injections and can cause significant side effects.
A single 600 mcg morning injection is not equivalent to 300 mcg twice daily, even though the arithmetic is the same
In TRIUMPH-3, retatrutide meaningfully reduced certain cardiovascular risk factors, with the highest dose delivering average reductions of 37.0% in triglycerides, 16.5% in non-HDL cholesterol, 9.3 mmHg in systolic blood pressure, 7.5 in (19.0 cm) in waist circumference, and 51.2% in high-sensitivity C-reactive protein (hsCRP)
This poses a significant risk, as unregulated peptides may be contaminated, improperly dosed, or ineffective
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