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Although the Food and Drug Administration (FDA) has only approved metformin for treating type 2 diabetes, healthcare providers also prescribe metformin off-label for several other purposes

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Single daily injections increase adherence in longer protocols

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In particular, because of the nature of chronic skin diseases, where long-term repetitive administration is essential, the development of platforms utilizing biodegradable polymers or bioderived materials (such as lipids and exosomes) that decompose into harmless byproducts and are excreted from the body after exerting therapeutic effects must be further strengthened