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Glucagon, secreted by pancreatic alpha cells, opposes insulin

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4,26 PLP deficiency has also been reported to be caused by displacement of pyridoxal phosphate from circulating albumin by acetaldehyde (an alcohol metabolite), which increases urinary excretion

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Estrogen may protect against cocaine-induced brain dysfunction by improving brain blood flow - progesterone and testosterone may be detrimental.(2001) www.sciencedaily.com From the article: Lead researcher Marc Kaufman and his colleagues first established the rate of blood flow to the brain in male and female occasional cocaine users