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This decline coincides with the skin's reduced capacity for repair and regeneration

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The role of dopamine and norepinephrine in depression and antidepressant treatment

Dopamine agonists, partial agonists and dopamine reuptake inhibitors (alone or in combination with serotonergic and noradrenergic agents) have shown some efficacy in treating mood symptoms and cognitive deficits and co-morbid symptoms of apathy and anxiety [46, 144]