Pay in 4 interest-free payments of $7.44 Learn more
Ships within 48 hours · Estimated delivery Aug 29 - Sep 3
FDA expands uses of Vyvanse to treat binge eating disorder
What they found (summary): Amylin is a critical partner of insulin in metabolism, the loss of amylin in T2DM is as significant as the loss of insulin The AMY1 receptor in the area postrema is the primary target for the appetite effect Amyloid aggregation is the main problem with native amylin, proline substitutions (the Pramlintide strategy) are essential The half-life of native amylin is only 13 minutes, that is why lipidated analogs like Cagrilintide are necessary Perspective: amylin + GLP-1 combinations are the natural evolution of metabolic pharmacotherapy Why it matters: This is the reference article for amylin pharmacology
But Trapps lab discovered a critical flaw: preproglucagon (PPG) neurons, which produce GLP-1 in the brainstem, lack receptors for circulating GLP-1
Right, and so they're going to pump them off to a urologist
What this means for HR and benefits leaders The stakes are high
US$ 20.14
US$ 26.78
US$ 23.53
US$ 25.89
US$ 22.82
