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Using a linear modeling approach and comparisons to a non-lipid accumulating strain, they were able to tease out some enzymes that regulate lipid accumulation independent to some extent of growth rate

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PlexusDx offers a Precision Peptide Genetic Test ($99 add-on or $298 standalone) that screens for key variants in these pathways

So in this case, if someone already has type 2 diabetes, they may be low in folate, and treatment with metformin may further drive a folate deficiency