Epidemiological data support an association between high dietary vitamin E intake and a reduced incidence of cardiovascular disease
Interestingly, basal GSH levels were not consistently affected by bME addition, cysteine addition, or the overexpression or inhibition of SLC7A11, which suggests that the amount of GSH in basal conditions is not a reliable marker of cell cystine uptake ability (Figures 4D, 5D and 6C)
Obese individuals with and without type 2 diabetes show different gut microbial functional capacity and composition
Existing combination therapies, such as phentermine/topiramate and naltrexone/bupropion, as well as the dual agonist tirzepatide, represent steps in this direction
However, its utility is limited by relatively low extraction yields and the risk of thermal degradation or isomerization of the target lactones due to prolonged exposure to high temperatures