Some people experience mild irritation during the initial adjustment period, particularly if they have sensitive skin or are using other active ingredients simultaneously
This direct delivery raises plasma concentrations within minutes, which is why IV remains the preferred route for therapeutic outcomes
Levine M, Conry-Cantilena C, Wang Y, Welch RW, Washko PW, Dhariwal KR et al (1996) Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance
The interesting part is its osmolarity and pH are closer to that of sub-epidermal tissues AND conjugation with various peptides such as Copper Tetrapeptide-1 (oka GHK-Cu) actually INCREASE rates of wound closure & wound healing b/w 282% and 548% (p Tissue repair, inflammation, skin quality, hair health
Here is a tabular representation to understand the difference between oral and liposomal glutathione: Clinical trials on liposomal glutathione show a 35% reduction in 8-isoprostane and a 20% improvement in the GSSG:GSH ratio
