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In diabetic male rats induced by streptozotocin treated with several antidiabetic drugs in order to evaluate their impact on the reproductive system, the authors reported a lack of sitagliptin effects on the structure and weight of the testis, epididymis and seminal vesicle as well as on T levels ( Instead, until now, only one male case-report on DPP4is effect on HPG axis has been reported with uncertain meaning
Xenograft study GBM cells (5 10 5 ) suspended in 5 l of DMEM were intracranially injected into female 4-week-old athymic nude mice (five mice/group) obtained from GemPharmatech (Nanjing, China)
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