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The absorption of vitamin B12 requires something called intrinsic factor, which is a protein found in stomach acid

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An early analysis of the results of 12 randomized controlled trials showed that folic acid supplementation (0.5-5 mg/day) had the greatest lowering effect on blood homocysteine concentrations (25% decrease)

[3] If you have concerns about the cost or availability of prescribed treatments, discuss this openly with your GP, who may be able to suggest alternatives or provide guidance on accessing medications through appropriate NHS channels