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doi: 10.1146/annurev-food-041715-033159 38 KeshteliA

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Within the hypothalamus, brain CPT1C serves as a sensor of nutrient availability by binding malonyl-CoA which triggers a reduction in the release of the appetite promoting neuropeptides, neuropeptide Y (NPY) and Agouti-related peptide (AgRP) and an increase in the release of the appetite suppressing neuropeptides, -melanocyte stimulating hormone (-MSH) and cocaine and amphetamine regulated transcript (CART)

development code PNB-0408) and Fosgonimeton (development code ATH-1017) are different molecules with different chemical structures and different pharmacokinetic profiles