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Conclusion In this study, we have identified a ~0.187% level of drug-tolerant persister cells with the CRC cell lines response to anticancer drugs, and we determined that there were G0/G1 cell cycle arrest, and upregulation of stemness factors and mesenchymal-like gene expression in the DTP cells

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Abstract Energy metabolism is indispensable for sustaining physiological functions in living organisms and assumes a pivotal role across physiological and pathological conditions

At physiological amounts, ROS participate in cellular signaling pathways and protect against infection and at physiological conditions cells are protected by effective antioxidant systems

Synergistic effects of free radical scavengers and cochlear vasodilators: a new otoprotective strategy for age-related hearing loss