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Psychiat Res

Conflicting results were observed from ERK5 kinase inhibitors, ERK5 PROTAC, and its genetic downregulation and depletion, and paradoxical activation of the transcriptional activity of ERK5 mediated by kinase inhibitors may contribute to these ambiguous results

mRNA expression levels were normalized to Gapdh, and relative expression was determined using the comparative Ct method (2Ct)

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